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The structural formula of propofol (2,6-diisopropylphenol), C12H18O. (Contributed by Dr. K K Jain.)
Aug. 05, 2020
Childhood Degenerative & Metabolic Disorders
GM1 gangliosidosis is a lysosomal storage disorder caused by a deficiency of beta-galactosidase-1. There are 3 phenotypes: infantile, juvenile, and adult. The infantile variant is the most severe form and results in neurologic impairment caused by accumulation of GM1 gangliosides, typically within the first 6 months of life. Other features include a macular cherry-red spot, coarse facies, and hepatosplenomegaly.
May. 25, 2019
May. 10, 2021
Oct. 12, 2020
Behavioral & Cognitive Disorders
Cognitive impairment is a common feature of multiple sclerosis and often leads to declines in the ability to initiate and carry out instrumental activities of daily living. Cognitive impairment in multiple sclerosis affects most cognitive domains, but processing speed, visual learning, and short-term memory deficits are most common. Neuropsychiatric symptoms are common, with lifetime prevalence rates of depression approaching 50%.
Jun. 09, 2020
Neuropharmacology & Neurotherapeutics
Sep. 04, 2021
Bell palsy is an acute, usually unilateral mononeuropathy of the seventh cranial nerve. The disorder is presumed to be inflammatory and associated with one of several different viral etiologies, usually herpes simplex virus-1. Features of Bell palsy include impairment of voluntary movement of facial and platysmal muscles, facial muscles pulled to the opposite side on smiling, saliva and food collected on the paralyzed side, and on attempting to close the eye, the eyeball is diverted upward and slightly outwards to avoid corneal exposure (Bell phenomenon).
Sep. 09, 2020
Mar. 10, 2021