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Late Stargardt disease

Late in Stargardt disease, the macula can take on a geographic atrophy appearance. Note the “flecks” in the retina of this patient. These are typical in Stargardt disease, but they can present in varying degree. (Contributed by Dr. James Walters.)

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Associated Disorders

  • Bassen-Kornzweig disease
  • Cushing syndrome
  • Kearns-Sayre syndrome
  • Lawrence-Moon-Biedl syndrome
  • Mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS)
  • Ocular paraneoplastic syndromes
  • Refsum disease
  • Usher syndrome
  • gastroesophageal reflux disease
  • posterior vitreous detachment
  • retinal detachment
  • systemic arterial hypertension
  • systemic lupus erythematosus