Neuropharmacology & Neurotherapeutics
Serotonin syndrome is due to the toxic effect of excess of serotonin activity. It may result from an overdose of serotonergic drugs as well as drug interactions, the most common of which occurs between serotonergic agents and MAO inhibitors. Clinical manifestations inlude mental status change, agitation, myoclonus, hyperreflexia, diaphoresis, shivering, tremor, diarrhea, incoordination, and fever.
Sep. 13, 2020