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BrainWaves #113 Teaching through clinical cases: Hypoactive delirium & antipsychotics

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021.

Originally released: June 21, 2018

This week's clinical case features a complex course of hospital-acquired delirium with an in-depth discussion on antipsychotics. Dr. Ayyappan Venkatraman reviews the pertinent psychopharmacology in dopaminergic and nondopaminergic signaling.

Produced by James E Siegler. Music by Unheard Music Concepts, Kevin McLeod, Lee Rosevere, and Steve Combs. BrainWaves' podcasts and online content are intended for medical education only and should not be used for clinical decision-making.


Jeste DV, Caligiuri MP. Tardive dyskinesia. Schizophr Bull 1993;19(2):303-15. PMID 8100643

Lacasse H, Perreault MM, Williamson DR. Systematic review of antipsychotics for the treatment of hospital-associated delirium in medically or surgically ill patients. Ann Pharmacother 2006;40(11):1966-73. PMID 17047137

O'Keeffe ST, Lavan JN. Clinical significance of delirium subtypes in older people. Age Ageing 1999;28(2):115-9. PMID 10350406

We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

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