Sign Up for a Free Account
  • Updated 07.29.2021
  • Released 09.07.2007
  • Expires For CME 07.29.2024



Historical note and terminology

Dopamine agonists have been shown to be effective in delaying levodopa-induced dyskinesia in early Parkinson disease, but intermittent administration of short-acting dopaminergic agents can predispose Parkinson disease patients to motor fluctuations. Rotigotine, a non-ergot dopamine D2 agonist, has antiparkinsonian effects when infused intravenously, and a transdermal preparation is now available as rotigotine constant delivery system (CDS), which allows a constant delivery of the drug. This is a significant development in the treatment of Parkinson disease. In addition to an improved safety profile and symptomatic effectiveness, transdermal rotigotine can simplify treatment for physicians as well as patients. It is particularly useful for patients with dysphagia who have difficulty swallowing oral medications. It was approved in the United States by the FDA in 2007.

This is an article preview.
Start a Free Account
to access the full version.

  • Nearly 3,000 illustrations, including video clips of neurologic disorders.

  • Every article is reviewed by our esteemed Editorial Board for accuracy and currency.

  • Full spectrum of neurology in 1,200 comprehensive articles.

  • Listen to MedLink on the go with Audio versions of each article.

Questions or Comment?

MedLink®, LLC

3525 Del Mar Heights Rd, Ste 304
San Diego, CA 92130-2122

Toll Free (U.S. + Canada): 800-452-2400

US Number: +1-619-640-4660



ISSN: 2831-9125