Chorea in Wilson disease

Multiple sclerosis: clinical aspects

Multiple sclerosis (MS) lesions in the brain and spinal cord damage every function of the central nervous system. Clinical symptoms vary from mild to aggressive; the course can be relapsing-remitting or progressive, and the symptoms and course evolve over time. Protean symptoms include fatigue and disturbed sensory, motor, bladder, bowel, sexual, cerebellar, brainstem, optic nerve, and cognitive realms.