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This infant girl with glutaric aciduria displays axial dystonia in the form of opisthotonic posturing. (Contributed by Dr. Joseph Jankovic.)
Headache & Pain
Oct. 11, 2020
General Child Neurology
Extracerebral fluid collections in infants are common and of multiple etiologies. Most acute subdural hematomas occur non-accidentally. Infections can
Jan. 19, 2021
Paroxysmal dyskinesias are a relatively rare subset of hyperkinetic movement disorders that are defined by their episodic nature. They may be categorized into paroxysmal kinesigenic dyskinesia, paroxysmal nonkinesigenic dyskinesia, and paroxysmal exertion-induced dyskinesia. Paroxysmal dyskinesias may be sporadic, genetic, or caused by metabolic or structural etiologies. Another common cause of paroxysmal dyskinesias is psychogenic movement disorders.
Feb. 15, 2021
Neuropharmacology & Neurotherapeutics
Sep. 05, 2021
Sleep is a powerful enhancer of epileptic features. Synchronized non-REM sleep facilitates seizures, whereas desynchronized REM sleep dampens seizure occurrence. The presence of nocturnal seizures affects the regular profile of the sleep architecture. Sleep-related seizures mostly affect conventional sleep measures, whereas nocturnal interictal discharges basically have a destabilizing impact on cyclic alternating pattern parameters.
Jan. 28, 2020
Sep. 27, 2020
Epilepsy & Seizures
Atonic seizures are epileptic attacks characterized by a sudden loss or diminution of muscle tone, which may be fragmentary, confined to a segment, or massive, leading to a slumping to the ground. They may have a generalized or focal origin, and may be brief (drop seizures) with patients able to stand up immediately if they fall; or prolonged (akinetic seizures), lasting from one to several minutes, where the patient falls to the ground and remains mute and motionless.
Aug. 01, 2019
Cell adhesion molecules (CAMs) are a diverse family of extracellular (eg, laminin) and cell surface (eg, NCAM) glycoproteins involved in cell-cell and
Mar. 05, 2021