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Computed tomography angiogram of the aortic arch and carotid bifurcations. (Contributed by Dr. Brian Silver.)
Nov. 17, 2020
This article includes discussion of tibial nerve injuries and Morton neuroma. The foregoing terms may include synonyms, similar disorders, variations in
Jun. 07, 2021
Childhood Degenerative & Metabolic Disorders
Oct. 21, 2020
Celiac disease is a genetic autoimmune disease triggered by exposure and reaction to gluten, with evidence of enteropathy on small intestinal biopsy. It can lead to an array of clinical symptoms, with up to 22% of patients exhibiting neurologic or psychiatric symptoms, most commonly ataxia and peripheral neuropathy. Rarer complications include epilepsy and myopathy.
Mar. 26, 2018
Stroke & Vascular Disorders
Atrial fibrillation is the most common sustained cardiac arrhythmia and the most common cause of cardioembolism. It confers a 3- to 5-fold increase in stroke risk and accounts for 15% to 30% of all ischemic strokes. Patients present with severe deficits and clinical evidence of cortical or cerebellar dysfunction. The most current guidelines for the prevention of stroke recommend the correction of modifiable vascular risk factors.
Jan. 18, 2021
Headache & Pain
Migraine aura without headache consists of visual, sensory, or speech symptoms such as photopsia, teichopsia, scotoma, visual distortion, numbness, weakness, or difficulty hearing or speaking. Cortical spreading depression, glutamatergic neurotransmission, channelopathies, neuronal-glial gap-junction communications, endothelial disfunctions, and microembolization may play a role in pathogenesis.
Jan. 05, 2020
Jul. 21, 2021
Neuropharmacology & Neurotherapeutics
Neurotrophic factors play an important role in the survival and maintenance of neurons. There are considerable experimental data on various neurotrophic factors in relation to peripheral neuropathies, which forms the basis of therapeutic interventions. There is some evidence of efficacy of neurotrophic factors in diabetic neuropathy in clinical trials and in anticancer agent-induced peripheral neuropathy, but no further clinical trials in are progress.
Sep. 02, 2020