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Multifocal subacute punctate supratentorial white matter lesions in man with Susac syndrome (MRI)

Axial brain DWI in a 22-year-old man diagnosed with Susac syndrome, showing multifocal subacute punctate supratentorial white matter lesions (black arrows) with the most prominent lesion affecting the posterior corpus callosum (red arrowhead). The study also showed T2/FLAIR hyperintensities involving the deep gray nuclei as well as leptomeningeal enhancement (not shown). (Source: Gertner E, Rosenbloom MH. Susac syndrome with prominent dermatological findings and a prompt response to intravenous immunoglobulin, steroids, and rituximab: a case report. J Med Case Rep 2016;10[1]:137. Creative Commons Attribution 4.0 International [CC BY 4.0] license,

Associated Disorders

  • Cerebral microinfarcts
  • Deafness
  • Encephalopathy
  • Retinal arterial occlusion
  • Retinopathy