This is an image preview.
Start a Free Account
to view the full image.

Sign Up for a Free Account For information on discounts, see Plans & Pricing

Nearly 3,000 illustrations, including video clips of neurologic disorders.
Every article is reviewed by our esteemed Editorial Board for accuracy and currency.
Full spectrum of neurology in 1,200 comprehensive articles.
Listen to MedLink on the go with Audio versions of each article.

Entry of B6 vitaminers into a cell

Download

To enter a cell, phosphorylated vitamers are hydrolyzed by tissue-nonspecific alkaline phosphatase (ALPL). Once inside the cell, pyridoxal kinase phosphorylates the different vitamers, yielding pyridoxine-5’-phosphate (PNP), pyridoxamine 5’-phosphate (PMP), and pyridoxal 5′-phosphate (PLP). Legend: ALPL, tissue-nonspecific alkaline phosphatase; PDXK, pyridoxal kinase; PDXP, pyridoxal phosphatase; PL, pyridoxal; PLP, pyridoxal 5′-phosphate; PM, pyridoxamine; PMP, pyridoxamine 5’-phosphate; PN, pyridoxine; PNP, pyridoxine-5’-phosphate. (Contributed by Dr. Douglas Lanska.)