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Bone spicules in retinitis pigmentosa

With degeneration of the retinal pigment epithelium, pigment is liberated. This pigment tends to align itself with the small retinal venules and takes on the appearance of “bone spicules.” (Contributed by Dr. Rosa Ana Tang.)

Associated Disorders

  • Bassen-Kornzweig disease
  • Cushing syndrome
  • Kearns-Sayre syndrome
  • Lawrence-Moon-Biedl syndrome
  • Mitochondrial encephalopathy with lactic acidosis and stroke-like episodes (MELAS)
  • Ocular paraneoplastic syndromes
  • Refsum disease
  • Usher syndrome
  • gastroesophageal reflux disease
  • posterior vitreous detachment
  • retinal detachment
  • systemic arterial hypertension
  • systemic lupus erythematosus