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Unverricht-Lundborg disease (photomicrograph)

Semithin epoxy resin section from a skin biopsy of a patient with progressive myoclonic epilepsy type 1 (EPM1). Marked vacuolation involves eccrine secretory cells but spares myoepithelial cells (arrows) and a nearby eccrine duct (D). (x770) (Contributed by Dr. Frederick Andermann.)