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Investigation of critical care unit patients who have weakness of limb and respiratory muscles (algorithm)

NMJ = neuromuscular junction, bx = biopsy, CK = creatine kinase, CIP = critical illness polyneuropathy, GBS = Guillain-Barré syndrome, MG = myasthenia gravis, LEMS = Lambert-Eaton myasthenia syndrome. (Adapted with permission from: Bolton CF. Critical illness polyneuropathy. In: Thomas PK, Asbury A, editors. Peripheral Nerve Disorders II. Oxford, UK: Butterworth-Heinemann, 1995:262-70.)

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Associated Disorders

  • Asthma
  • COPD exacerbation
  • Critical illness and injury
  • Gram-negative sepsis
  • Neuromuscular blockade
  • Organ transplantation
  • Sepsis
  • Septic encephalopathy
  • Septic shock
  • Steroid myopathy
  • Systematic inflammatory response syndrome