Management of chronic neuromuscular disease in children
Feb. 24, 2021
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Muscle biopsy in mildly affected muscles shows variation of fiber size, thin atrophic fibers, central nuclei, internal structural changes, and endomysial fibrosis. In the tibialis anterior muscle, there are frequently rimmed vacuoles (though this is not a consistent finding) and rare necrotic fibers. Rimmed vacuoles can be seen in other muscles. (Contributed by Dr. Duaa Jabari.)