Diagnosis of childhood immune-mediated CNS vasculitides
Aug. 31, 2021
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Axial T1-weighted (left) and T2-weighted (right) MRI images of a 6-year-old child with the PEHO phenotype caused by CCDC88A truncating mutation demonstrating reduced brain volume with bilateral, severe pachygyria/lissencephaly. (Source: Nahorski MS, Asai M, Wakeling E, et al. CCDC88A mutations cause PEHO-like syndrome in humans and mouse. Brain 2016;139(Pt 4):1036-44. Creative Commons Attribution License.)