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Paget disease of bone (lateral skull x-rays)

(A) A lateral skull x-ray demonstrating the well defined large area of radiolucency representing the edge of an osteolytic margin (identified by the arrowheads) in Paget disease of bone calvarial involvement; these changes are referred to as osteoporosis circumscripta. (B) A lateral skull x-ray demonstrating the “cotton-wool” appearance seen with diffuse calvarial pagetoid bone involvement, accompanied by an expanded diploic space and cortical bone thickening. (X-rays provided as a courtesy by Loyola University Medical Education Network.)

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