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Progressive multifocal leukoencephalopathy (photomicrograph)

Photomicrograph of multifocal leukoencephalopathy lesion, stained with antibody to JC virus capsid antigen. Numerous oligodendrocytes are positive for the presence of JC virus (white arrows). Several bizarre astrocytes are also present; these are negative for JC virus capsid antigen (green arrows). (Contributed by Dr. John Greenlee.)

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