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Cerebral wall in a 26-week fetus with Potter sequence (photomicrograph)

The cortex (C) shows abnormal lamination with many neuron-deficient columns in its upper part. In areas where the plane of section is near transverse, the tangentially cut neuronal columns look like islets of cells surrounded by a cell-deficient neuropil, giving a glomerular appearance (as seen on the right). The underlying white matter (W) shows many arrested heterotopic neurons (arrows), trapped along their migration corridors. (Magnification x20, cresyl violet staining) (Contributed by Dr. Hazim Kadhim.)