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This MRI shows infarction in the right middle cerebral artery territory in a patient with sickle cell anemia. (Contributed by Dr. Robert Adams.)
Jul. 20, 2020
Amyloidosis refers to the extracellular deposition of fibrils composed of low weight chain of a variety of normal serum proteins. The autosomal dominant hereditary transthyretin amyloidosis (hATTR) and the acquired light chain (AL)-amyloidosis, the result of a plasma cell dyscrasia, are the 2 most common types of amyloidosis associated with peripheral neuropathy. In both, the main presentation is a painful, length-dependent small fiber neuropathy starting in the feet, with numbness, burning and allodynia, which can be particularly worse at night.
Feb. 12, 2020
Multiple sclerosis is caused by immune attack against brain cells, with damage from demyelination and destruction of oligodendroglia, along with damage to axons and neurons. Cortical disruption affects cognition and multiple central nervous system functions. MS differs from other autoimmune diseases in that there is no proven target antigen.
Jul. 18, 2017
Dec. 26, 2019
Dec. 31, 2020
Blepharospasm is characterized by involuntary eye closure, along with contractions of other facial muscles, oromandibular dystonia, and sometimes cervical dystonia. Excessive contractions of the eyelids, orbicularis oculi adjacent muscles, jaw and neck muscles cause these symptoms. It is a focal dystonia of idiopathic origin.
Mar. 18, 2020
Epilepsy & Seizures
Apr. 01, 2021
Headache & Pain
Cluster headache is a primary headache disorder characterized by severe, unilateral pain that is orbital, supraorbital, or temporal and 15 minutes to 3 hours in duration occuring 1 to 8 times a day. There are 2 major forms of cluster headache: episodic and chronic. Accompanying symptoms include ipsilateral: conjunctival injection, lacrimation, nasal congestion, rhinorrhea, facial sweating, eyelid edema, and miosis.
Jan. 17, 2021