New Books in Neuroscience: Adrian Keith Perkel, "Unlocking the Nature of Human Aggression: A Psychoanalytic and Neuroscientific Approach" (Routledge, 2023)

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Listen here to New Books in Neuroscience, a podcast from New Books Network featuring interviews with neuroscientists about their new books. For more information, visit New Books in Neuroscience.

Originally released: March 12, 2025

Today I began my discussion with Dr. Adrian Perkel about his new book Unlocking The Nature of Human Aggression: A Psychoanalytic and Neuroscientific Approach (Routledge, 2024)

“Aggression is to the mind what the immune system is to the body. It doesn’t seek the fight.” With this perfect mind-body analogy Dr. Perkel proposes a clear way to think theoretically and work clinically with aggression. Throughout the book he links Freud’s formulations of the psyche with contemporary physics and biochemistry. Perkel’s assertion that “Where the aggressive drive goes, so therein lies the solution to many of the psychological problems that present to us in life” is broadly summarized in three essential points:

1. The aggressive drive in the human psyche has the aim of reducing stimuli and excitations brought on by internal and external impingements - it is not looking for a fight.

2. What constitutes a threat or impingement is not necessarily objective - in fact it is always filtered through subjective experience and the UCS associations that are revisited repeatedly giving rise to a lens through which experience is filtered.

3. This experience is driven by memory traces of experience that embed themselves in the UCS and are revisited and hence enacted in a repetitive manner.

“My argument is that what wraps all those three points together is that you have life drive needs yes but they're often unfulfilled they're often frustrated and then we need a second mechanism which is what Freud called the death drive.” Acknowledging that the death drive is contentious in psychoanalysis “in neuroscience it's not contested.”

I knew going into this interview that we would only discuss a few concepts and elaborations from his book. For more of Dr. Perkel’s writing and webinar on this book please go here and here.

We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode’s original release date.