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  • Updated 06.22.2023
  • Released 03.05.1999
  • Expires For CME 06.22.2026

Drug-induced disturbances of smell and taste



Many drugs produce disturbances of smell and taste. In some cases, symptoms resolve on discontinuation of the offending medication, whereas others are persistent and impair quality of life. This article reviews pathogenetic mechanisms, differential diagnosis, and management of drug-induced disturbances of smell and taste.

Key points

• Many drugs from different pharmacological categories have been associated with disturbances of taste and smell.

• Treatment of smell and taste disturbances is mostly limited to zinc supplementation and discontinuation or dose reduction of the offending drug.

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