Hereditary neuropathy with predisposition to pressure palsy
Nov. 09, 2023
At vero eos et accusamus et iusto odio dignissimos ducimus qui blanditiis praesentium voluptatum deleniti atque corrupti quos dolores et quas.
Thallium poisoning is still a source of toxic exposure. Dermatologic changes along with alopecia are key clues to the diagnosis of this painful neuropathy. In this article, the author reviews the clinical and laboratory features.
• Alopecia is one of the clues to thallium poisoning, as it is almost always present.
• Thallium neuropathy is usually predominately sensory, affecting both small fibers (pain) and large fibers (ataxia).
Pesticides and rodenticides based on thallous salts were commonly used in the past. Although they are rarely used now, poisoning from accidental (mostly children), suicidal, or homicidal ingestion continues to occur (22; 26). Although industrial occupations may result in exposure to thallium, this is usually low level and chronic, rather than acute and high level (08). Consumption of contaminated food and water (17; 12) may also be a source of intoxication. Thallium intoxication has also been reported with contaminated drugs, including heroin and cocaine (01).
Nearly 3,000 illustrations, including video clips of neurologic disorders.
Every article is reviewed by our esteemed Editorial Board for accuracy and currency.
Full spectrum of neurology in 1,200 comprehensive articles.
Listen to MedLink on the go with Audio versions of each article.