Neuropharmacology & Neurotherapeutics
Sep. 06, 2020
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What is tick paralysis?
Tick Paralysis is caused by over 40 species of ticks worldwide (5 in North America, including the deer tick) and can occur in almost any region where ticks are found. It has killed thousands of animals, mainly cows and sheep, in other parts of the world. Although tick paralysis is of concern in domestic animals and livestock in the United States as well, human cases are rare and usually occur in children under the age of 10.
Tick paralysis occurs when an engorged and gravid (egg-laden) female tick produces a neurotoxin in its salivary glands and transmits it to its host during feeding. Experiments have indicated that the greatest amount of toxin is produced between the fifth and seventh day of attachment (often initiating or increasing the severity of symptoms), although the timing may vary depending on the species of tick.
Unlike Lyme disease, ehrlichiosis, and babesiosis, which are caused by the systemic proliferation and expansion of parasites in their hosts long after the offending tick is gone, tick paralysis is chemically induced by the tick and can therefore continue only in its presence. Once the tick is removed, symptoms usually diminish rapidly. However, in some cases, profound paralysis can develop and even become fatal before anyone becomes aware of a tick's presence.
Where is tick paralysis prevalent?
Ticks that cause tick paralysis are found in almost every region of the world. In the United States, most reported cases have occurred in the Rocky Mountain states, the Pacific Northwest and parts of the South. The five North American species of ticks thought to cause tick paralysis are widely distributed throughout the United States; therefore, the potential for contact with such ticks exists in every state.
Symptoms of tick paralysis generally begin from five to seven days after a tick becomes attached (usually on the scalp), beginning with fatigue, numbness of the legs and muscle pains. Paralysis rapidly develops from the lower to the upper extremities and, if the tick is not removed, is followed by tongue and facial paralysis. The most severe complications may include convulsions, respiratory failure and, in up to 12% of untreated cases, death.
Because of the inability of laboratory tests to indicate tick paralysis, diagnosis is based on symptomology and the rapid improvement of the patient once the engorged tick is removed.
Treatment is simply removing the feeding tick(s). It is important to remove all the mouthparts, since they contain the salivary glands which may continue to infect the patient even after the body of the tick has been removed.
To remove a tick, follow these steps:
• Using a pair of pointed precision* tweezers, grasp the tick by the head or mouthparts right where they enter the skin. DO NOT grasp the tick by the body.
• Without jerking, pull firmly and steadily directly outward. DO NOT twist the tick out or apply petroleum jelly, a hot match, alcohol or any other irritant to the tick in an attempt to get it to back out.
• Place the tick in a vial or jar of alcohol to kill it.
• Clean the bite wound with disinfectant.
*Keep in mind that certain types of fine-pointed tweezers, especially those that are etched, or rasped, at the tips, may not be effective in removing nymphal deer ticks. Choose unrasped fine-pointed tweezers whose tips align tightly when pressed firmly together.
Then, monitor the site of the bite for the appearance of a rash beginning 3 to 30 days after the bite. At the same time, learn about the other early symptoms of Lyme disease and watch to see if they appear in about the same timeframe. If a rash or other early symptoms develop, see a physician immediately.
Prevention & control
As with all other tick-borne diseases, the most effective precautions against tick paralysis are to avoid walking through or brushing against vegetation and to perform daily self-examinations for ticks - even in the fall and winter months.
If you live in regions with higher incidences of tick paralysis (see Where is Tick Paralysis Prevalent? above) and spend a lot of time outdoors, wearing long pants, long-sleeved shirts, socks and enclosed shoes may reduce a tick's chances of contacting your skin. Insect repellents containing the active ingredient DEET can be applied to the skin (be sure to strictly follow the manufacturer's directions) or to the clothes, while Permethrin can only be used on clothing. Hikers should stay on cleared, well-worn trails to avoid contact with vegetation.
Most importantly, no matter where you live, inspect yourself thoroughly after returning from any outing, even if you go no further than the front lawn. Prompt removal of ticks, preferably before they've had a chance to become engorged, will go a long way in preventing tick paralysis and other tick-borne diseases.
This information was developed by the American Lyme Disease Foundation, Inc and is herewith used with permission.
American Lyme Disease Foundation, Inc. Tick Paralysis. Available at: https://www.aldf.com/tick-paralysis/. Accessed September 6, 2018.
The information in this document is for general educational purposes only. It is not intended to substitute for personalized professional advice. Although the information was obtained from sources believed to be reliable, MedLink Corporation, its representatives, and the providers of the information do not guarantee its accuracy and disclaim responsibility for adverse consequences resulting from its use. For further information, consult a physician and the organization referred to herein.