Negative myoclonus in Lafora disease (video-EEG)

ALS-like disorders of the Western Pacific

Amyotrophic lateral sclerosis-parkinsonism-dementia complex (ALS-PDC), also known as lytico-bodig, is an endemic neurodegenerative disorder of the Western Pacific islands. It is a slowly progressive degenerative disease with a spectrum of clinical presentation that can include features of amyotrophic lateral sclerosis, parkinsonism, and dementia. The cycad-derived toxin cycasin as well as the neurotoxic nonprotein amino acid beta-methyl-amino-L-alanine have been postulated as potential etiologies.

Locked-in syndrome

Rehabilitation of spinal cord injury

Patients with new spinal cord injuries have unique challenges that are best addressed in an inpatient rehabilitation setting. The patient’s functional goals should be based on their level of injury. There are multiple medical issues the physician should evaluate and patients should familiarize themselves with, including pain, spasticity, neurogenic bowel or bladder, pressure injuries, autonomic dysreflexia, and pulmonary compromise.