Aug. 17, 2022
Nearly 3,000 illustrations, including video clips of neurologic disorders.
Every article is reviewed by our esteemed Editorial Board for accuracy and currency.
Full spectrum of neurology in 1,200 comprehensive articles.
Listen to MedLink on the go with Audio versions of each article.
This 18-year-old girl has Unverricht-Lundborg disease that began at 12 years of age with action myoclonus and generalized tonic-clonic seizures. Despite major antimyoclonic therapy, including valproate, phenobarbital, benzodiazepine,s and piracetam 27 g/day, she is markedly handicapped by major myoclonic jerks elicited by action, intention of action, or even any cutaneous stimuli. There is also a pseudo-cerebellar syndrome with the finger-to-nose maneuver and marked photosensitivity. (Courtesy of Professor Pierre Thomas from: The Educational Kit on Epilepsies. Volume 2: Idiopathic Generalised Epilepsies With Myoclonic Jerks. Oxford: Medicinae, 2007.)