Neuro-Oncology
Neurofibromatosis 1 and intracranial neoplasms of childhood
Mar. 04, 2022
This is an image preview.
Start a Free Account
to view the full image.
-
Nearly 3,000 illustrations, including video clips of neurologic disorders.
-
Every article is reviewed by our esteemed Editorial Board for accuracy and currency.
-
Full spectrum of neurology in 1,200 comprehensive articles.
-
Listen to MedLink on the go with Audio versions of each article.
Unverricht-Lundborg disease clinical manifestations
This 18-year-old girl has Unverricht-Lundborg disease that began at 12 years of age with action myoclonus and generalized tonic-clonic seizures. Despite major antimyoclonic therapy, including valproate, phenobarbital, benzodiazepine,s and piracetam 27 g/day, she is markedly handicapped by major myoclonic jerks elicited by action, intention of action, or even any cutaneous stimuli. There is also a pseudo-cerebellar syndrome with the finger-to-nose maneuver and marked photosensitivity. (Courtesy of Professor Pierre Thomas from: The Educational Kit on Epilepsies. Volume 2: Idiopathic Generalised Epilepsies With Myoclonic Jerks. Oxford: Medicinae, 2007.)