Neuropharmacology & Neurotherapeutics
Neuroprotection for CNS disorders
Mar. 21, 2021
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In the physiological state, inside the lysosome, alpha-galactosidase A catalyzes the hydrolysis of glycosphingolipids, with terminal alpha-galactose residues in the course of sphingolipid degradation. (Source: Amodio F, Caiazza M, Monda E, et al. An overview of molecular mechanisms in Fabry disease. Biomolecules 2022;12:1460. Creative Commons Attribution [CC BY] license, creativecommons.org/licenses/by/4.0.)