Alpha-ketoglutarate dehydrogenase deficiency
May. 19, 2023
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A 97-year-old man presenting with acute-onset “vascular” Korsakoff syndrome with bilaterally damaged mammillothalamic tracts. T2-weighted images revealed a microbleed scar over the left mammillothalamic tract. (Source: Yoneoka Y, Seki Y, Akiyama K. "Vascular" Korsakoff syndrome with bilaterally damaged mammillothalamic tracts: insights into the pathogenesis of "acute" Korsakoff syndrome as acute-onset irreversible anterograde amnesia. Cureus 2021;13(11):e19472. Creative Commons Attribution License [CC-BY 4.0]. Edited by Dr. Douglas J Lanska.)