Progressive supranuclear palsy: cognitive and behavioral changes
Aug. 16, 2022
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A 97-year-old man presenting with acute-onset “vascular” Korsakoff syndrome with bilaterally damaged mammillothalamic tracts. In the enlarged images, (A) infarction is shown over the right mammillothalamic tract; (B) a microbleed is shown over the left mammillothalamic tract; and (C) FLAIR image shows both the acute, ischemic lesion of the right mammillothalamic tract and the old left mammillothalamic tract lesion. (Source: Yoneoka Y, Seki Y, Akiyama K. "Vascular" Korsakoff syndrome with bilaterally damaged mammillothalamic tracts: insights into the pathogenesis of "acute" Korsakoff syndrome as acute-onset irreversible anterograde amnesia. Cureus 2021;13(11):e19472. Creative Commons Attribution License [CC-BY 4.0].)