Periodic paralysis and related disorders
Episodes of periodic paralysis typically involve generalized muscle weakness with hypotonia and areflexia but spare bulbar and respiratory muscles and cognition. During attacks, affected muscles are in a state of sustained depolarization and are electrically inexcitable. Attacks may last minutes, hours, or even days. Episodes are often precipitated by specific triggers (behavior/diet) or are associated with abnormal serum potassium levels.
Dec. 05, 2019