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Each lesion represents a separate nidus of infection that has disseminated from the initial site of inoculation (Contributed by Dr. John Halperin.)
Jul. 17, 2021
This article includes discussion of Andermann syndrome, agenesis of corpus callosum with polyneuropathy, corpus callosum agenesis with sensorimotor neuropathy,
Aug. 15, 2017
Facioscapulohumeral muscular dystrophy can manifest with protruding scapulae, difficulty raising the arms (often asymmetrically) and lifting objects, and progresses to include truncal muscles as well as lower extremity muscles. About 20% of patients are wheelchair dependent after age 50. Inheritance is autosomal dominant in most with a high incidence of sporadic cases due to de novo mutations.
Dec. 28, 2020
Jul. 02, 2020
Hepatic encephalopathy is a potentially reversible metabolic disturbance of the brain in liver disease. The most common cause is cirrhosis of the liver, but other hepatotoxic agents may lead to hepatic encephalopathy. Manifestations range from minimal cognitive deficits to stupor and coma. Most of the cases can be managed medically, but liver transplant is required in some cases.
Jul. 03, 2021
Neuropharmacology & Neurotherapeutics
Transcranial magnetic stimulation involves noninvasive stimulation of the cerebral cortex using externally applied magnetic fields and has been used extensively for the investigation, diagnosis, and management of neurologic disorders. Favorable results have been reported in the treatment of depression, epilepsy, Parkinson disease, multiple sclerosis, stroke rehabilitation, and chronic pain. Further studies are needed for establishing the efficacy and safety of transcranial magnetic stimulation.
Apr. 01, 2021
Jan. 05, 2021
Progressive systemic sclerosis is a condition associated with thickening of the skin and tethering to subcutaneous tissues as well as smooth muscle atrophy and fibrosis of internal organs such as the gastrointestinal tract, lungs, heart, and kidneys. Pain symptoms are common in patients with systemic sclerosis and are independently associated with more frequent episodes of Raynaud phenomenon, active ulcers, and worsening synovitis.
Apr. 24, 2021