3525 Del Mar Heights Rd, Ste 304San Diego, CA 92130-2122
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Retina section from patient with Walker-Warburg syndrome showing focus of abnormal proliferated retinal epithelium (arrow). (Contributed by Dr. Peter Barth.)
Headache & Pain
Aug. 19, 2021
Childhood Degenerative & Metabolic Disorders
Aug. 03, 2021
Neuropharmacology & Neurotherapeutics
High-dose intravenous immune globulin (IVIG) has been used for the treatment of autoimmune disorders since 1981, starting with idiopathic thrombocytopenic purpura. IVIG is a safe and effective therapy for Guillain-Barré syndrome, but some cases may not respond to it or may get worse. IVIG is the preferred first-line treatment for chronic inflammatory demyelinating polyradiculoneuropathy and an adjunctive therapy for myasthenia gravis where no other therapy is effective.
Mar. 08, 2021
Behavioral & Cognitive Disorders
Olfactory deficits involving odor detection, identification, and discrimination are very common early in the course of Parkinson disease and dementia with Lewy bodies. Odor identification is also impaired in patients with REM sleep behavior disorder, a common and very early feature of Lewy body alpha-synucleinopathies. Less commonly, some degree of olfactory loss has also been reported in various other dementing disorders, including Alzheimer disease and frontotemporal dementia.
Oct. 21, 2020
Sequelae of whiplash injuries include neck and back injuries, headaches, dizziness, paresthesias, weakness, visual symptoms, and cognitive, somatic, and psychological sequelae. Rear-end collisions can cause a hyperextension-flexion neck injury, with common whiplash symptoms generally attributable to soft tissue injuries. Chronic or late whiplash syndrome refers to persistent symptoms present more than 6 months after the accident.
Aug. 07, 2021
Childhood primary headaches are increasingly being recognized as a significant neurologic health problem. According to a study by the AMPP, the migraine prevalence in adolescents is 14%. Early diagnosis and an integrative treatment approach are essential to minimize the impact on a child's quality of life. Differentiating primary headaches from those caused by underlying, perhaps life-threatening pathology is critical to expedient establishment of appropriate treatment and, potentially, cure.
Aug. 22, 2021
Neurofibromatosis 2 is a tumor predisposition syndrome most commonly associated with the development of multiple schwannomas (classically bilateral vestibular schwannomas), meningiomas, and ependymomas. Most adult patients present with symptoms of hearing loss, tinnitus, and impaired balance. Children more commonly present with visual symptoms such as strabismus, cataract, visual loss, or proptosis, and sometimes unilateral facial nerve paralysis or seizures.
Mar. 07, 2018
Mar. 11, 2021