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Neocortex in Walker-Warburg syndrome (photomicrograph)

The cortex in Walker-Warburg syndrome typically features complete loss of laminar structure, with neurons appearing in clusters and vertical streaks, often grouped around penetrating leptomeningeal vessels. (Hematoxylin-eosin; original magnification x4) (Contributed by Dr. Peter Barth.)

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Associated Disorders

  • Agyria
  • Brain malformation
  • Buphthalmos
  • Cataract
  • Cerebellar malformation
  • Congenital muscular dystrophy
  • Corneal opacity
  • Dandy-Walker syndrome
  • Encephalocele
  • Glaucoma
  • Hydrocephalus
  • Lissencephaly
  • Microphthalmos
  • Optic nerve atrophy
  • Retinal detachment
  • Retinal dysplasia