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Severe hydrocephalus due to Walker-Warburg syndrome in young boy (MRI)

T1-weighted inversion recovery MRI of a 4-month-old male with severe hydrocephalus due to Walker-Warburg syndrome. In this section, the border between cortex and adjacent white matter is irregular because of the irregular structure of the neocortex, a characteristic of cobblestone malformation. (Contributed by Dr. Peter Barth.)

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Associated Disorders

  • Agyria
  • Brain malformation
  • Buphthalmos
  • Cataract
  • Cerebellar malformation
  • Congenital muscular dystrophy
  • Corneal opacity
  • Dandy-Walker syndrome
  • Encephalocele
  • Glaucoma
  • Hydrocephalus
  • Lissencephaly
  • Microphthalmos
  • Optic nerve atrophy
  • Retinal detachment
  • Retinal dysplasia