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Neonatal Alexander disease at 9 months of age follow-up (post-contrast MRI)

Many regions show contrast enhancement, including parts of the white matter, mainly periventricular, the basal ganglia, brainstem, and dentate nuclei. (Contributed by Dr. Amy Waldman.)

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Associated Disorders

  • Dysautonomia
  • Gastrointestinal reflux disease
  • Palatal myoclonus
  • Seizures and epilepsy
  • Sleep apnea
  • Spasticity
  • Urinary dysfunction