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Juvenile Alexander disease at 10 years of age (sagittal MRI)

The enhancing lesion is seen in the dorsal medulla on this sagittal post-gadolinium T1 image. (Contributed by Dr. Amy Waldman.)

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Associated Disorders

  • Dysautonomia
  • Gastrointestinal reflux disease
  • Palatal myoclonus
  • Seizures and epilepsy
  • Sleep apnea
  • Spasticity
  • Urinary dysfunction