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Axial FLAIR image showing extensive involvement of the thalami bilaterally in a patient with acute disseminated encephalomyelitis. (Contributed by Dr. Brenda Banwell.)
Epilepsy & Seizures
Feb. 16, 2020
Neuro-Ophthalmology & Neuro-Otology
Alexia without agraphia is a dramatic disorder of higher visual function in which patients can still write but are unable to read. It may be either a disconnection syndrome or a selective word form visual agnosia. Alexia without agraphia is due to the language cortex being cut off from visual input and is usually associated with visual agnosia and prosopagnosia but may also occur in isolation.
Oct. 07, 2020
Neurologic involvement of Behcet disease appears as a vascular-inflammatory CNS disease with focal or multifocal parenchymal involvement. A less common form includes isolated cerebral venous sinus thrombosis and intracranial hypertension. Behcet's is characterized by oral or genital ulcers, eye inflammation, and skin lesions.
Sep. 01, 2020
Infection of the central nervous system caused by free-living amoebae is rare but usually lethal. Granulomatous amebic encephalitis is a subacute infection
Jun. 08, 2020
MELAS is characterized by stroke-like episodes typically occurring before age 40, encephalopathy with seizures and/or dementia, and mitochondrial myopathy. Recurrent headache, loss of appetite, or recurrent vomiting are early symptoms. It is a multisystem genetic disorder usually beginning in childhood.
Jan. 11, 2021
Headache & Pain
Although usually benign, headache can herald serious intracranial disease. Neuroimaging must be considered whenever secondary causes of headache are suspected. The “SNOOP-4” mnemonic provides a list of red flags that would suggest secondary headache and indicate a need for further evaluation, usually with neuroimaging. Neuroimaging should also be strongly considered in unusual primary headaches.
In this update, the author summarizes advances in the understanding of genetic underpinnings of focal epilepsy due to DEPDC5 mutations, with evidence
Apr. 03, 2021