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Vastus lateralis muscle biopsy of a 9-year-old boy (1)

Paraffin transverse sections stained with hematoxylin-eosin show normal muscle architecture, no connective tissue proliferation, necrosis, or regeneration, and two populations of fibers by size. Magnification of A is x100, and magnification of B is x250. (Contributed by Dr. Harvey Sarnat.)

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Associated Disorders

  • Calpain 3 deficiency
  • Cerebellar hypoplasia
  • Cori-Forbes disease
  • Debrancher enzyme deficiency
  • Emery-Dreifuss X-linked muscular dystrophy
  • Krabbe globoid cell leukodystrophy
  • Mitochondrial cytopathies
  • Moebius syndrome
  • Multiple sulfatase deficiencies
  • Myasthenia gravis, congenital
  • Nemaline rod myopathy
  • PHOX2B mutation
  • Pompe disease
  • Trendelenburg gait
  • Ullrich (collagen VI) muscular dystrophy