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Breast cancer metastatic to the sphenoid and ethmoid bones with direct extension into the orbital apex (CT)

Axial CT section through the orbits displayed in bone window. A permeative partially osteoblastic metastasis involves the sphenoid and the ethmoid bones on the right. Direct extension of abnormal soft tissue from this bony lesion into the orbital apex occurs, resulting in proptosis and orbital apex syndrome. (Contributed by Dr. Zubair Shaikh.)

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Associated Disorders

  • Breast carcinoma
  • Collet-Sicard syndrome
  • Colon cancer
  • Garcin or hemibase syndrome
  • Jackson syndrome
  • Jugular foramen syndrome (Vernet syndrome)
  • Lung carcinoma
  • Middle fossa (Gasserian ganglion) or Raeder paratrigeminal syndrome
  • Numb chin syndrome
  • Occipital condyle syndrome
  • Orbital syndrome
  • Parasellar or cavernous sinus syndrome
  • Prostate carcinoma
  • Renal cell carcinoma
  • Schmidt syndrome
  • Tapia syndrome
  • Thyroid carcinoma
  • Villaret syndrome