Basal ganglia: functional anatomy and neuropharmacology
Nov. 21, 2020
Nearly 3,000 illustrations, including video clips of neurologic disorders.
Every article is reviewed by our esteemed Editorial Board for accuracy and currency.
Full spectrum of neurology in 1,200 comprehensive articles.
Listen to MedLink on the go with Audio versions of each article.
Sagittal T1-weighted MR image of a 22-year-old woman from 1988 shows a normal sagittal sinus (A), whereas MR image from 1992 shows a clot within the sagittal sinus. Patient had marked and progressive increase in intracranial pressure with loss of vision, despite heparin therapy, and was subsequently treated with multiple doses of intravenous tissue plasminogen activator. Patient's condition and thrombus formation stabilized, but the thrombus did not resolve despite thrombolytic therapy. Optic nerve fenestrations and finally a lumbar-peritoneal shunt successfully relieved symptoms of increased intracranial pressure. (Used with permission. JP Broderick. Cerebral venous thrombosis. In: Feldman E, editor. Current diagnosis in neurology. St. Louis: Mosby, 1994.)