Sign Up for a Free Account

This is an image preview.
Start a Free Account
to view the full image.

  • Nearly 3,000 illustrations, including video clips of neurologic disorders.

  • Every article is reviewed by our esteemed Editorial Board for accuracy and currency.

  • Full spectrum of neurology in 1,200 comprehensive articles.

  • Listen to MedLink on the go with Audio versions of each article.

Abnormal subcortical white matter in a patient afflicted with CADASIL

Under normal conditions, Luxol fast blue stains myelinated axons blue. In this patient with CADASIL, there is a large patch of subcortical white matter (outlined with arrows), which fails to stain blue, reflecting ischemia-induced axonal and myelin loss. The cerebral cortex (CC) is stained pink and appears healthy. (Contributed by Dr. Steve Moore and Dr. Jill Hagenkord of the University of Iowa Department of Pathology.)

Related Media

Associated Disorders

  • Familial hemiplegic migraine
  • Subcortical stroke
  • Transient ischemic attack