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Neuropharmacology & Neurotherapeutics
Mar. 21, 2021
Neuro-Ophthalmology & Neuro-Otology
Headaches, transient visual obscurations, and pulsatile tinnitus are the most frequent early manifestations of idiopathic intracranial hypertension (IIH) in adults. Untreated, it can result in optic nerve injury, visual field defects, and blindness. The manifestations of IIH in children differ from those in adults and include asymptomatic papilledema, prominent neck or back pain, diplopia, torticollis, and other focal neurologic signs.
Sep. 02, 2019
Carbon monoxide poisoning can produce several nonspecific symptoms and can mimic several diseases. Most of the effects are due to hypoxia. Neurologic sequelae are significant and may be delayed in onset. Hyperbaric oxygen plays an important role in the management of carbon monoxide poisoning.
Mar. 28, 2021
Neck pain, with or without radiating arm pain and associated root distribution paraesthesias, numbness, and motor deficit, is the classic presenting feature of cervical disc disease. The rupture of disc material through the annulus presents as an irritative mass against the centrally positioned spinal cord or laterally positioned root.
Jun. 23, 2021
Jul. 07, 2021
Spinal muscular atrophy (SMA) is a neurodegenerative disorder primarily affecting the anterior horn cells. Signs of motor neuron disease such as muscle weakness, muscle atrophy, fasciculations, and reduced or absent deep tendon reflexes can be seen. There is a broad phenotypic spectrum of SMA ranging from more severely affected infants who are symptomatic at birth to ambulatory adults who develop proximal weakness late in life.
Jul. 05, 2019
Peripheral neurolymphomatosis is a rare neurologic manifestation of non-Hodgkin lymphoma in which peripheral nerve infiltration of lymphoma cells is a dominant feature both clinically and pathologically. Affected neural structures include peripheral nerves, spinal nerve roots, cranial nerves, and plexus, commonly with multiple site involvement. Neurolymphomatosis is also reported as a relapse of intravascular large B-cell lymphoma.
Feb. 25, 2021
Toxoplasma gondii is a widely distributed protozoan that is found in multiple animal species. Human infection is common, and may result in lifelong persistence of the organism. Initial infection is usually asymptomatic but can result in a syndrome of fever, lymphadenopathy, and splenomegaly closely resembling infectious mononucleosis. Neurotoxoplasmosis is largely limited to immunocompromised individuals, in particular patients with HIV.
Jan. 31, 2021