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QTc prolongation and anteroseptal injury pattern in hypocalcemic myopathy secondary to idiopathic hypoparathyroidism

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A 12-lead electrocardiogram of a 45-year-old woman showing a QTc interval of 486 ms (suggestive of borderline prolongation) and a pattern of acute anteroseptal injury. She presented in a wheelchair with complaints of generalized body aches and progressive weakness of both legs for 3 to 4 days. Chvostek’s and Trousseau’s signs were negative. Investigations revealed severe hypocalcemia (serum calcium 4.5 mg/dL) with inappropriately low-normal parathyroid hormone levels. ECG showed QTc prolongation and anteroseptal injury pattern. Her final diagnosis was hypocalcemic myopathy secondary to idiopathic hypoparathyroidism. (From: Aloke A, Singh K. An unusual presentation of multifactorial hypocalcemia as myopathy: a case report. Cureus 2025;17[7]:e87434. Creative Commons Attribution 4.0 International [CC BY 4.0] license, creativecommons.org/licenses/by/4.0.)