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Dysgenesis of the corpus callosum in fetal alcohol syndrome (MRI)

MRI scan of 8-month-old with fetal alcohol syndrome. (A) T1-weighted midsagittal image demonstrates a hypoplastic corpus callosum (arrow). All other brain structures appear normal. (B) Flair axial section demonstrates absence of the corpus callosum at a rostro-caudal level in which a corpus callosum would normally be present. The lateral ventricles are moderately enlarged, but there is no evidence of obstructive hydrocephalus. (C) T1-weighted coronal image demonstrates bundles of Probst (arrows), white matter bundles aborted in their attempt to cross the midline. (Contributed by Dr. Daniel Bonthius.)

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Associated Disorders

  • Attention deficit hyperactivity
  • Conduct disorders
  • Congenital heart disease
  • Epilepsy
  • Genital anomalies
  • Learning disorders
  • Microcephaly