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Chondrosarcomas are typified by cords of cells with mucin. They are differentiated from chordomas by immunohistochemical staining. (Contributed by Dr. Jason A Heth.)
Jan. 11, 2021
Sydenham chorea is the most common cause of acute chorea in children worldwide and is characterized by a random and continuous flow of contractions that spreads rapidly and becomes generalized. Evidence suggests that Sydenham chorea results from Streptococcus-induced antibodies that cross-react with central nervous system antigens. Neuropsychiatric symptoms, such as obsessions, compulsions, hyperactivity, and attention disorder, as well as depression, are often present in patients with Sydenham chorea.
Apr. 07, 2021
Epilepsy & Seizures
Oct. 02, 2020
Physiologic changes during pregnancy, including a relative hypercoagulable state, hormonal changes, and shifts in vascular volume, can trigger central nervous system complications. The risk of ischemic and hemorrhagic stroke is increased in the peripartum and postpartum periods, related to venous thrombosis, reversible cerebral vasoconstriction, and preeclampsia/eclampsia.
Aug. 14, 2021
Jun. 30, 2021
Behavioral & Cognitive Disorders
When assessing memory at the bedside, we are examining 4 subtypes of memory: immediate memory, working memory, recent memory, and remote memory. The most common presentations in the clinical setting are mild cognitive impairment, Alzheimer disease, vascular dementia, dementia with Lewy bodies, Wernicke-Korsakoff syndrome, and chronic traumatic encephalopathy. Abnormal markers of both amyloid and tau are necessary for the occurrence of the accelerated neurodegeneration and memory loss that precedes Alzheimer disease.
Jul. 23, 2020
General Child Neurology
Child maltreatment, which includes child abuse and neglect, is a major public health concern that can lead to significant lifelong psychological and
Jan. 04, 2016
Epilepsy with generalized tonic-clonic seizures alone is probably a syndrome of idiopathic/genetic generalized epilepsy but of uncertain boundaries. Onset is usually in late adolescence, and genetic predisposition is common. Generalized onset tonic-clonic seizures may occur at any time, though those happening after awakening are more characteristic and better studied. Prognosis is markedly variable.
Feb. 19, 2020