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Paragangliomas are composed of trabeculae or balls of cells with an abundant vascular pattern. (Contributed by Dr. Jason A Heth.)
General Child Neurology
Apr. 20, 2020
Headache & Pain
Headaches associated with intracranial neoplasms are common. In this article, the epidemiology, pathogenesis, and clinical presentation of brain tumor-associated
Apr. 21, 2020
Monoclonal gammopathy (IgG, IgM, or IgA) is identified in 10% of patients with idiopathic neuropathy. Approximately half of these associations are coincidental given the prevalence of monoclonal gammopathies in the general population. Peripheral neuropathy and monoclonal gammopathy may be the presenting features of a plasma cell dyscrasia (preneoplastic disorders). Patients with nonmalignant monoclonal gammopathy should be followed carefully; malignant transformation occurs at a rate of 1.5% per year.
Nov. 05, 2020
The myotonic dystrophies (MD) are the commonest cause of adult-onset muscular dystrophy. Two distinct entities have been described: myotonic dystrophy type 1 (DM1) and myotonic dystrophy type 2 (DM2). Some important differences in the phenotypes of DM1 and DM2 include the presence or absence of congenital form, muscles primarily affected (distal vs. proximal), involved muscle fiber types (type 1 vs. type 2 fibers), and some associated multisystemic phenotypes.
Oct. 16, 2020
Corticobasal degeneration (CBGD) is one of the atypical parkinsonian syndromes or Parkinsonism-plus syndromes that can mimic Parkinson disease, but it is distinct because of the added features of apraxia, dysphasia, cortical sensory signs, unusual dystonic postures, involuntary movements such as myoclonus, and “alien limb” sign. The pathological hallmark is the deposition of abnormally hyper-phosphorylated microtubule associated protein tau in various parts of the brain. CBGD inevitably progresses slowly and is invariably fatal.
Jan. 31, 2021
Jan. 05, 2021
Dec. 07, 2004
Mar. 26, 2021