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Paragangliomas are composed of trabeculae or balls of cells with an abundant vascular pattern. (Contributed by Dr. Jason A Heth.)
Mar. 08, 2021
Migraine headaches, cluster headaches, paroxysmal hemicrania, hypnic headache, and headache on awakening are the most emblematic sleep-related headache disorders. Migraine headaches may be provoked by sleep, but the most common association is sleep following a migraine attack. Migraine research has revealed mediating signaling molecules such as serotonin and dopamine that are common with sleep.
Apr. 21, 2021
Neuro-Ophthalmology & Neuro-Otology
Pupil abnormalities encompass afferent and efferent types, including unequal size, light near dissociation, irregular shape, abnormal position, and episodic abnormalities. They can be transient or constant, and are often asymptomatic or noticed by an observer.
Feb. 13, 2020
Testing directly for LGI1 and contactin-associated protein 2 (CASPR2) antibodies should be undertaken in patients with clinical features suggestive of faciobrachial dystonic seizures, limbic encephalitis, Morvan syndrome, and neuromyotonia. LGI1-antibody seropositivity is most commonly associated with limbic encephalitis, with a high incidence of seizures and cognitive impairment. There is significant overlap in clinical manifestations with CASPR2 seropositivity, with neuromyotonia, pain, and sleep disturbance occurring across both clinical entities, albeit at different frequencies.
Jun. 08, 2020
Neuropharmacology & Neurotherapeutics
There is no satisfactory method for treating glioblastoma. Gene therapy is one of the promising innovative approaches. Some gene therapy strategies such as RNA interference may enhance the effect of concomitant chemotherapy. Innovative strategies for glioblastoma that are promising include targeted gene therapy delivered by nanoparticles.
Aug. 24, 2021
Behavioral & Cognitive Disorders
Feb. 11, 2020
Infection of the central nervous system caused by free-living amoebae is rare but usually lethal. Granulomatous amebic encephalitis is a subacute infection
The thoracic outlet syndromes include true neurogenic, disputed, arterial, venous, and traumatic neurovascular subtypes, which all feature the compression of neurovascular structures in the thoracic outlet. The true neurogenic variety is extremely rare, and is characterized by sensory symptoms over the medial hand or forearm and intrinsic hand muscle weakness and atrophy.
Sep. 13, 2021