Acute disseminated encephalomyelitis
Acute disseminated encephalomyelitis (ADEM) is an inflammatory demyelinating disorder predominantly affecting white and gray matter in the brain and spinal cord. Clinical presentation includes encephalopathy (which may manifest as behavioral change, profound irritability, or altered consciousness) that cannot be explained by fever and polyfocal neurologic deficits. Systemic symptoms such as fever, headache, and fatigue often precede the development of neurologic deficits.
May. 06, 2020