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Striatal dopamine release changes in writer’s cramp

Differences in endogenous striatal dopamine release as measured by displacement of [11C]raclopride (RAC ΔBP) in patients with writer’s cramp compared to healthy controls during a right-hand finger tapping task (A) and speech production task (B). RAC ΔBP findings (green) are overlaid with striatal regions found to have reduced D2/D3 receptor availability at rest (yellow) and one cluster shown where these findings overlap in the left putamen (red). (Contributed by Dr. Brian Berman.)

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  • Parkinson disease
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  • Progressive supranuclear palsy
  • Tourette syndrome