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Sotos syndrome facial features

Patient with Sotos syndrome at the age of (A) 3 years old, (B) 7 years old, and (C) 11 years old. Note the distinctive facial features, including macrocephaly, dolichocephaly, hypertelorism with downslanting palpebral fissures, anteverted nostrils, frontal bossing, pointed chin, and prominent mandible. (Contributed by Dr. Ghada M H Abdel-Salam.)

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