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Pathologic section from a fatal case of carbon monoxide poisoning reported by German physician and military hygienist Heinrich Ruge (1896-1977)

"Completely fatty small artery in a focus of softening. Details of the brain substance cannot be recognized anymore." Death occurred 10 days after poisoning. Staining with Sudan and hematoxilin (Sudan dyes, which are used to stain lipids, dissolve in droplets containing triglycerides and color them intensely). (Source: Case 9 from: Ruge H. Kasuistischer Beitrag zur pathologischen Anatomie der symmetrischen Linsenkernerweichung bei CO-Vergiftung [Casuistic contribution to the pathological anatomy of symmetric softening of the lens nucleus in CO poisoning]. Archiv für Psychiatrie und Nervenkrankheiten 1922;64:150-205.)

Associated Disorders

  • Anoxic leukoencephalopathy
  • Carbon monoxide-induced parkinsonism
  • Delayed carbon monoxide encephalopathy
  • Late sequelae of carbon monoxide poisoning
  • Warehouse workers headache