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Colorimetric change in a solution of blood with a progressively greater content of carboxyhemoglobin

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A solution of normal blood (top), normal blood shaken with coal gas (containing a mixture of hydrogen, methane, carbon monoxide, and ethylene) (middle), and the blood of one of the fatalities of a coal mine explosion in Britain (bottom). The progressively saturated red color was due to the increasing content of carboxyhemoglobin. (Source: Haldane JS. Report to the secretary of state for the home department on the causes of death in colliery explosions and underground fires, with special reference to the explosions at Tylorstown, Brancepeth, and Micklefield. London: Printed for Her Majesty's Stationery Office, by Eyre and Spottiswoode, 1896a.)